Our group has a long-standing interest in developing new techniques and reagents for facilitating the study of the retina and hypothalamus. 

Working together with other groups at Hopkins, we have developed the HuProt human proteome array, which currently contains over 23,000 unique full-length proteins, and a collection of over 1400 HuProt-validated immunoprecipitation-grade monoclonal antibodies against human transcription factors. 

Recently, we have also co-developed a range of new computational tools for identifying evolutionarily conserved gene regulatory networks from single-cell RNA and ATAC-Seq data sets.

Other techniques developed in the lab include:

PanoView: An Iterative Clustering Approach for Analysis of Single-cell RNA-Sequencing Data

A toolbox of immunoprecipitation-grade monoclonal antibodies to human transcription factors

The NIH Protein Capture Reagents Program (PCRP): a standardized protein affinity reagent toolbox