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Blackshaw Lab

Building and Rebuilding the Retina and Hypothalamus

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Category: <span>Development</span>

Rax regulates hypothalamic tanycyte differentiation and barrier function in mice

Development, Radial glia, Tanycytes, Transcription factor

Miranda-Angulo AM, Byerly MS, Wang H, Messa J, Blackshaw S. J Comp Neurol 2013, 522:876-99.

Link to Article>> View PDF>>

Lhx2 is required for positioning of the eye field and patterning of the hypothalamus

Development, Hypothalamus, Lhx2, Retina, Spatial patterning

Roy A, de Melo J, Chaturvedi D, Thein T, Cabrera-Socorro A, Meyer G, Blackshaw S, Tole S. J Neurosci 2013 33:6877-84.

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The long noncoding RNA Six3OS acts in trans to regulate retinal development by modulating Six3 activity

Cell fate, Development, Retina, Transcription factor

Rapicavoli NA, Poth EM, Zhu H and Blackshaw S. Neural Dev 2011 6:23

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Sall3 controls retinal cone photoreceptor and horizontal cell development

Cell fate, Development, Photoreceptor, Retina, Transcription factor

De Melo J, Peng G-H, Chen S and Blackshaw S. Development 2011 138:2325-36.

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A genomic atlas of mouse hypothalamic development

Development, Hypothalamus, Neurogenesis, Shh, Spatial patterning, Thalamus, Transcription factor, Transcriptomics

Shimogori T, Lee D A, Miranda-Angulo A, Yang Y, Yoshida A, Jiang L, Kataoka A, Wang H, Mashiko H, Avetisyan M A, Qi L, Qian J, and Blackshaw S. Nat Neurosci 2010 13:767-75.

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The long noncoding RNA RNCR2 directs mouse retinal cell specification

Cell fate, Development, lncRNAs, Retina

Rapicavoli N, Poth E, Blackshaw S. BMC Dev Biol 2010 10:49

Link to Article>>

Pias3 directs rod photoreceptor development via SUMOylation of Nr2e3

Cell fate, Development, Photoreceptor, SUMOylation, Transcription factor

Onishi A, Peng GH, Du CH, Alexis U, Chen S, Blackshaw S. Neuron 2009 61:234-46.

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New meaning in the message: noncoding RNAs and their role in retinal development

Development, lncRNAs, Review article

Rapicavoli NA, Blackshaw S. Dev Dynam, 2009 238:2103-14.

Link to Article>>

Molecular pathways controlling development of thalamus and hypothalamus: from neural specification to circuit formation

Development, Hypothalamus, Review article

Blackshaw S, Scholpp S, Placzek M, Ingraham H, Simerly R, Shimogori T. J Neurosci. 2010 30:14925-30.

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Development of vertebrate retina and hypothalamus

Development, Hypothalamus, Retina, Review article

Byerly MS, Blackshaw S. Wiley Interdisciplinary Reviews: Systems Biology and Medicine, 2009 1:380-9.

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Research Areas

  • AAV
  • Antibody specificity
  • ATAC-Seq
  • Autoimmune disease
  • Behavior
  • Book Chapter
  • Cell fate
  • Cell lineage analysis
  • Chemical senses
  • Chemogenetics
  • ChIP-Seq
  • Circadian
  • Commentary
  • D-Amino acids
  • Development
  • Diabetes
  • Extraretinal photoreceptors
  • FGF
  • Human genetics
  • Hypothalamus
  • In vivo electroporation
  • Lens
  • Lhx2
  • lncRNAs
  • Metabolism
  • Muller glia
  • Neural circuitry
  • Neural development
  • Neurodegeneration
  • Neurogenesis
  • Neurotransmitters
  • New technique
  • Nitric oxide
  • Notch/Delta
  • Nucleogenesis
  • Photoreceptor
  • Protein microarray
  • Proteomics
  • Protocol
  • Radial glia
  • Retina
  • Review article
  • RNA binding proteins
  • RNA splicing
  • RPE
  • SAGE
  • scRNA-Seq
  • Shh
  • Signal transduction
  • Sleep
  • Spatial patterning
  • SUMOylation
  • Suprachiasmatic nucleus
  • Tanycytes
  • Thalamus
  • Transcription factor
  • Transcriptomics
  • Visual cycle
  • Wnt

Recent Posts

  • Cell-specific regulation of gene expression using splicing-dependent frameshifting
  • Ectopic insert-dependent neuronal expression of GFAP promoter-driven AAV constructs in adult mouse retina
  • LRLoop: A method to predict feedback loops in cell-cell communication
  • Notch Inhibition Promotes Regeneration and Immunosuppression Supports Cone Survival in a Zebrafish Model of Inherited Retinal Dystrophy
  • Genetic loss of function of Ptbp1 does not induce glia-to-neuron conversion in retina

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