LRLoop: A method to predict feedback loops in cell-cell communication

Xin, Y., Lyu, P., Jiang, J., Zhou, F., Wang, J., Blackshaw, S., & Qian, J. (2022). LRLoop: A method to predict feedback loops in cell-cell communication. Bioinformatics (Oxford, England)38(17), 4117–4126. Advance online publication. https://doi.org/10.1093/bioinformatics/btac447

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Notch Inhibition Promotes Regeneration and Immunosuppression Supports Cone Survival in a Zebrafish Model of Inherited Retinal Dystrophy

Fogerty, J., Song, P., Boyd, P., Grabinski, S. E., Hoang, T., Reich, A., Cianciolo, L. T., Blackshaw, S., Mumm, J. S., Hyde, D. R., & Perkins, B. D. (2022). Notch Inhibition Promotes Regeneration and Immunosuppression Supports Cone Survival in a Zebrafish Model of Inherited Retinal Dystrophy. The Journal of neuroscience : the official journal of the Society for Neuroscience42(26), 5144–5158. https://doi.org/10.1523/JNEUROSCI.0244-22.2022

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Genetic loss of function of Ptbp1 does not induce glia-to-neuron conversion in retina

Hoang, T., Kim, D. W., Appel, H., Pannullo, N. A., Leavey, P., Ozawa, M., Zheng, S., Yu, M., Peachey, N. S., & Blackshaw, S. (2022). Genetic loss of function of Ptbp1 does not induce glia-to-neuron conversion in retina. Cell reports39(11), 110849. https://doi.org/10.1016/j.celrep.2022.110849

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In vivo base editing rescues cone photoreceptors in a mouse model of early-onset inherited retinal degeneration

Choi, E. H., Suh, S., Foik, A. T., Leinonen, H., Newby, G. A., Gao, X. D., Banskota, S., Hoang, T., Du, S. W., Dong, Z., Raguram, A., Kohli, S., Blackshaw, S., Lyon, D. C., Liu, D. R., & Palczewski, K. (2022). In vivo base editing rescues cone photoreceptors in a mouse model of early-onset inherited retinal degeneration. Nature communications13(1), 1830. https://doi.org/10.1038/s41467-022-29490-3

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Cell-specific cis-regulatory elements and mechanisms of non-coding genetic disease in human retina and retinal organoids

Thomas, E. D., Timms, A. E., Giles, S., Harkins-Perry, S., Lyu, P., Hoang, T., Qian, J., Jackson, V. E., Bahlo, M., Blackshaw, S., Friedlander, M., Eade, K., & Cherry, T. J. (2022). Cell-specific cis-regulatory elements and mechanisms of non-coding genetic disease in human retina and retinal organoids. Developmental cell57(6), 820–836.e6. https://doi.org/10.1016/j.devcel.2022.02.018

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Quantitative transportomics identifies Kif5a as a major regulator of neurodegeneration

Shah, S. H., Schiapparelli, L. M., Ma, Y., Yokota, S., Atkins, M., Xia, X., Cameron, E. G., Huang, T., Saturday, S., Sun, C. B., Knasel, C., Blackshaw, S., Yates, J. R., Cline, H. T., & Goldberg, J. L. (2022). Quantitative transportomics identifies Kif5a as a major regulator of neurodegeneration. eLife11, e68148. https://doi.org/10.7554/eLife.68148

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Cross-species transcriptomic and epigenomic analysis reveals key regulators of injury response and neuronal regeneration in vertebrate retinas

Hoang TV, Wang J, Boyd P, Wang F, Santiago C, Jiang L, Lahne M, Todd LJ, Saez C, Yoo S, Keuthan C, Palazzo I, Squires N, Campbell WA, Jia M, Rajaii F, Parayil T, Wang G, Ash J, Fischer AJ, Hyde DR, Qian J, Blackshaw S.

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