Disruption of stromal hedgehog signaling initiates RNF5-mediated proteasomal degradation of PTEN and accelerates pancreatic tumor growth

Pitarresi JR, Liu X, Avendano AA, Sizemore GM, Cuitiño MC, Kladney RD, Mace TA, Chang JJ, Ennis CS, Reeves R, Blackshaw S, Zhang J, Yu L, Fernandez SA, Frankel WL, Bloomston M, Rosol TJ, Lesinski GB, Konieczny SF, Wu J, Gustavo Leone G, Song JW, and Ostrowski MC. Life Sci Alliance 2018 1:e201800190.

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