LRLoop: A method to predict feedback loops in cell-cell communication

Cell fate, Development, Neural development, Neurogenesis, Retina, scRNA-Seq, , , , ,

Xin, Y., Lyu, P., Jiang, J., Zhou, F., Wang, J., Blackshaw, S., & Qian, J. (2022). LRLoop: A method to predict feedback loops in cell-cell communication. Bioinformatics (Oxford, England), 38(17), 4117–4126. Advance online publication. https://doi.org/10.1093/bioinformatics/btac447

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Notch Inhibition Promotes Regeneration and Immunosuppression Supports Cone Survival in a Zebrafish Model of Inherited Retinal Dystrophy

Muller glia, Neurodegeneration, Neurogenesis, Notch/Delta, Photoreceptor, Retina, scRNA-Seq, , , , , ,

Fogerty, J., Song, P., Boyd, P., Grabinski, S. E., Hoang, T., Reich, A., Cianciolo, L. T., Blackshaw, S., Mumm, J. S., Hyde, D. R., & Perkins, B. D. (2022). Notch Inhibition Promotes Regeneration and Immunosuppression Supports Cone Survival in a Zebrafish Model of Inherited Retinal Dystrophy. The Journal of neuroscience : the official journal of the Society for Neuroscience, 42(26), 5144–5158. https://doi.org/10.1523/JNEUROSCI.0244-22.2022

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Genetic loss of function of Ptbp1 does not induce glia-to-neuron conversion in retina

Cell lineage analysis, Muller glia, Neurogenesis, Retina, RNA binding proteins, , , ,

Hoang, T., Kim, D. W., Appel, H., Pannullo, N. A., Leavey, P., Ozawa, M., Zheng, S., Yu, M., Peachey, N. S., & Blackshaw, S. (2022). Genetic loss of function of Ptbp1 does not induce glia-to-neuron conversion in retina. Cell reports, 39(11), 110849. https://doi.org/10.1016/j.celrep.2022.110849

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Loss of Function of the Neural Cell Adhesion Molecule NrCAM Regulates Differentiation, Proliferation and Neurogenesis in Early Postnatal Hypothalamic Tanycytes

Development, Hypothalamus, Neural development, Neurogenesis, scRNA-Seq, Tanycytes, , , , ,

Moore, A., Chinnaiya, K., Kim, D. W., Brown, S., Stewart, I., Robins, S., Dowsett, G., Muir, C., Travaglio, M., Lewis, J. E., Ebling, F., Blackshaw, S., Furley, A., & Placzek, M. (2022). Loss of Function of the Neural Cell Adhesion Molecule NrCAM Regulates Differentiation, Proliferation and Neurogenesis in Early Postnatal Hypothalamic Tanycytes. Frontiers in neuroscience, 16, 832961. https://doi.org/10.3389/fnins.2022.832961

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Cross-species transcriptomic and epigenomic analysis reveals key regulators of injury response and neuronal regeneration in vertebrate retinas

Neural development, Neurodegeneration, Neurogenesis, Retina, scRNA-Seq, Transcriptomics

Hoang TV, Wang J, Boyd P, Wang F, Santiago C, Jiang L, Lahne M, Todd LJ, Saez C, Yoo S, Keuthan C, Palazzo I, Squires N, Campbell WA, Jia M, Rajaii F, Parayil T, Wang G, Ash J, Fischer AJ, Hyde DR, Qian J, Blackshaw S.

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