Hypothalamus Archives - Blackshaw Lab

Loss of Function of the Neural Cell Adhesion Molecule NrCAM Regulates Differentiation, Proliferation and Neurogenesis in Early Postnatal Hypothalamic Tanycytes

Development, Hypothalamus, Neural development, Neurogenesis, scRNA-Seq, Tanycytesdevelopment, Hypothalamus, neural development, neurogenesis, scRNA-Seq, tanycytes

Moore, A., Chinnaiya, K., Kim, D. W., Brown, S., Stewart, I., Robins, S., Dowsett, G., Muir, C., Travaglio, M., Lewis, J. E., Ebling, F., Blackshaw, S., Furley, A., & Placzek, M. (2022). Loss of Function of the Neural Cell Adhesion Molecule NrCAM Regulates Differentiation, Proliferation and Neurogenesis in Early Postnatal Hypothalamic Tanycytes. Frontiers in neuroscience, 16, 832961. https://doi.org/10.3389/fnins.2022.832961

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Single cell RNA-Seq analysis identifies molecular mechanisms controlling hypothalamic patterning and differentiation

Hypothalamus, Neurogenesis, scRNA-Seq, Spatial patterning, TranscriptomicsHypothalamus, neurogenesis, scRNA-Seq, spatial patterning, transcriptomics

Kim DW, Washington PW, Wang ZQ, Lin S, Sun C, Jiang L, and Blackshaw S. Science, submitted.

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Winding the clock: development of hypothalamic neural circuitry controlling circadian timing and sleep

Circadian, Development, Hypothalamus, Review article, Sleep, Transcription factor

Kim DW and Blackshaw S. Masterclass in Developmental Neuroendocrinology, Springer, in press.

Ablation of tanycytes of the arcuate nucleus and median eminence increases visceral adiposity and decreases insulin sensitivity in male mice

Hypothalamus, Metabolism, Tanycytes

Yoo S, Cha D, Kim S, Jiang L, Adebesin M, Wolfe A, Riddle R, Aja S, and Blackshaw S. PNAS, under review.

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Tanycyte-independent regulation of hypothalamic leptin signaling

Hypothalamus, Metabolism, scRNA-Seq, Tanycytes

Yoo S, Cha D, Kim DW, Hoang T, and Blackshaw S. Frontiers in Neuroscience, in press.

Canonical Wnt signaling regulates patterning, differentiation and nucleogenesis in mouse hypothalamus and prethalamus

Development, Hypothalamus, Signal transduction, Spatial patterning, Wnt

Newman EA, Wu D, Makoto MM, Zhang J, and Blackshaw S. Dev Biol, e-pub ahead of print.

Foxd1 is required for terminal differentiation of anterior hypothalamic neuronal subtypes

Development, Hypothalamus, Spatial patterning, Transcription factor

Newman EA, Wan J, Wang J, Jiang, Qian J, and Blackshaw S. Dev Biol 2018 439:102-111

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Regulation and function of neurogenesis in adult mammalian hypothalamus

Hypothalamus, Neurogenesis, Tanycytes

Yoo S and Blackshaw S. Progress in Neurobiology 2018 170:53-66.

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Lhx6-positive GABAergic neurons of the zona incerta promote sleep

Chemogenetics, Hypothalamus, Neural circuitry, Sleep, Transcription factor

Liu K, Kim J, Kim DW, Zhang S, Denaxa M, Bao H, Lim SA, Kim E, Liu C, Wickersham IR, Pachinis V, Hattar S, Song J, Brown SR, and Blackshaw S. Nature 2017 548:582-587.

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An Lhx1-Regulated Transcriptional Network Controls Sleep-Wake Coupling and Thermal Resistance of the Central Circadian Clockworks

Circadian, Hypothalamus, Sleep

Bedont JL, LeGates TA, Buhr E, Bathini A, Ling J, Wong P, van Gelder R, Mongrain V, Hattar S, and Blackshaw S. Curr Biol 2017 27:128-136.

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Canonical Wnt signaling regulates patterning, differentiation and nucleogenesis in mouse hypothalamus and prethalamus

Foxd1 is required for terminal differentiation of anterior hypothalamic neuronal subtypes

Blackshaw Lab

Building and Rebuilding the Retina and Hypothalamus

Category: <span>Hypothalamus</span>

Loss of Function of the Neural Cell Adhesion Molecule NrCAM Regulates Differentiation, Proliferation and Neurogenesis in Early Postnatal Hypothalamic Tanycytes

Single cell RNA-Seq analysis identifies molecular mechanisms controlling hypothalamic patterning and differentiation

Winding the clock: development of hypothalamic neural circuitry controlling circadian timing and sleep

Ablation of tanycytes of the arcuate nucleus and median eminence increases visceral adiposity and decreases insulin sensitivity in male mice

Tanycyte-independent regulation of hypothalamic leptin signaling

Regulation and function of neurogenesis in adult mammalian hypothalamus

Lhx6-positive GABAergic neurons of the zona incerta promote sleep

An Lhx1-Regulated Transcriptional Network Controls Sleep-Wake Coupling and Thermal Resistance of the Central Circadian Clockworks