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Blackshaw Lab

Building and Rebuilding the Retina and Hypothalamus

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Category: <span>Hypothalamus</span>

Lhx2 is required for positioning of the eye field and patterning of the hypothalamus

Development, Hypothalamus, Lhx2, Retina, Spatial patterning

Roy A, de Melo J, Chaturvedi D, Thein T, Cabrera-Socorro A, Meyer G, Blackshaw S, Tole S. J Neurosci 2013 33:6877-84.

Link to Article>> View PDF>>

Hypothalamic Neuron-derived Neurotrophic Factor (NENF) interacts with BDNF and melanocortin signaling to modulate food intake

Hypothalamus, Metabolism, Signal transduction

Byerly MS, Swanson R, Kwon K, Aja S, Moran TH, Wong GW, Blackshaw S. Am J Physiol 2013 304:R1085-95.

Link to Article>>

Tanycytes of the median eminence form a dietary-responsive neurogenic niche

Cell lineage analysis, Hypothalamus, Metabolism, Neurogenesis, Radial glia, Tanycytes

Lee DA, Pak T, Bedont JL, Wang H, Miranda-Angulo A, Takiar V, Charubhumi V, Balordi F, Takebayashi H, Fishell G, Ford E and Blackshaw S. Nat Neurosci 2012 15:700-2.

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Functional Implications of Hypothalamic Neurogenesis in the Adult Mammalian Brain

Hypothalamus, Neurogenesis, Review article, Tanycytes

Lee DA, Blackshaw S. Int J Developmental Neuroscience, 2012 30:615-21.

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A genomic atlas of mouse hypothalamic development

Development, Hypothalamus, Neurogenesis, Shh, Spatial patterning, Thalamus, Transcription factor, Transcriptomics

Shimogori T, Lee D A, Miranda-Angulo A, Yang Y, Yoshida A, Jiang L, Kataoka A, Wang H, Mashiko H, Avetisyan M A, Qi L, Qian J, and Blackshaw S. Nat Neurosci 2010 13:767-75.

Link to Article>> View PDF>>

Molecular pathways controlling development of thalamus and hypothalamus: from neural specification to circuit formation

Development, Hypothalamus, Review article

Blackshaw S, Scholpp S, Placzek M, Ingraham H, Simerly R, Shimogori T. J Neurosci. 2010 30:14925-30.

Link to Article>> View PDF>>

Development of vertebrate retina and hypothalamus

Development, Hypothalamus, Retina, Review article

Byerly MS, Blackshaw S. Wiley Interdisciplinary Reviews: Systems Biology and Medicine, 2009 1:380-9.

Link to Article>>

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Research Areas

  • AAV
  • Antibody specificity
  • ATAC-Seq
  • Autoimmune disease
  • Behavior
  • Book Chapter
  • Cell fate
  • Cell lineage analysis
  • Chemical senses
  • Chemogenetics
  • ChIP-Seq
  • Circadian
  • Commentary
  • D-Amino acids
  • Development
  • Diabetes
  • Extraretinal photoreceptors
  • FGF
  • Human genetics
  • Hypothalamus
  • In vivo electroporation
  • Lens
  • Lhx2
  • lncRNAs
  • Metabolism
  • Muller glia
  • Neural circuitry
  • Neural development
  • Neurodegeneration
  • Neurogenesis
  • Neurotransmitters
  • New technique
  • Nitric oxide
  • Notch/Delta
  • Nucleogenesis
  • Photoreceptor
  • Protein microarray
  • Proteomics
  • Protocol
  • Radial glia
  • Retina
  • Review article
  • RNA binding proteins
  • RNA splicing
  • RPE
  • SAGE
  • scRNA-Seq
  • Shh
  • Signal transduction
  • Sleep
  • Spatial patterning
  • SUMOylation
  • Suprachiasmatic nucleus
  • Tanycytes
  • Thalamus
  • Transcription factor
  • Transcriptomics
  • Visual cycle
  • Wnt

Recent Posts

  • Cell-specific regulation of gene expression using splicing-dependent frameshifting
  • Ectopic insert-dependent neuronal expression of GFAP promoter-driven AAV constructs in adult mouse retina
  • LRLoop: A method to predict feedback loops in cell-cell communication
  • Notch Inhibition Promotes Regeneration and Immunosuppression Supports Cone Survival in a Zebrafish Model of Inherited Retinal Dystrophy
  • Genetic loss of function of Ptbp1 does not induce glia-to-neuron conversion in retina

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