Lhx2 regulates temporal changes in chromatin accessibility and transcription factor binding in retinal progenitor cells
Zibetti C, Liu S, Wan J, Qian J, Blackshaw S.
Epigenomic profiling of retinal progenitors reveals LHX2 is required for developmental regulation of open chromatin
Zibetti C, Liu S, Wan J, Qian J, and Blackshaw S. Comm Biology 2019, 2:142.
Ldb1 and Rnf12-dependent regulation of Lhx2 controls the relative balance between neurogenesis and gliogenesis in retina
de Melo J, Venkataraman A, Clark BS, Shiau F, Zibetti C, and Blackshaw S. Development 2018 145. pii: dev159970. doi: 10.1242/dev.159970
The stage-dependent roles of Ldb1 and functional redundancy with Ldb2 in mammalian retinogenesis
Gueta K, Cohen T, David A, Nobel H, Narkis G, Li L, Love P, de Melo J, Blackshaw S, Westphal H, and Ashery-Padan R. Development 2016 143:4182-4192.
Control of lens development by Lhx2- regulated neuroretinal FGFs
Thein T, de Melo J, Zibetti C, Clark BS, Juarez F, and Blackshaw S. Development 2016 143: 3994-4002.
Multiple intrinsic factors act in concert with Lhx2 to direct retinal gliogenesis
De Melo J, Clark BS, and Blackshaw S. Sci Reports 2016 6:32757.
Lhx2 Is an Essential Factor for Retinal Gliogenesis and Notch Signaling
De Melo J, Zibetti C, Clark BS, Hwang W, Miranda-Angulo AL, Qian J, Blackshaw S. J Neurosci 2016 36:2391-405.
The LIM homeodomain factor Lhx2 is required for hypothalamic tanycyte specification and differentiation
Salvatierra J, Lee DA, Zibetti C, Duran-Moreno M, Yoo S, Newman EA, Wang H, Bedont JL, de Melo J, Miranda-Angulo AL, Gil-Perotin S, Garcia-Verdugo JM, and Blackshaw S. J Neurosci 2014 34:16809-20.
Lhx2 is required for positioning of the eye field and patterning of the hypothalamus
Roy A, de Melo J, Chaturvedi D, Thein T, Cabrera-Socorro A, Meyer G, Blackshaw S, Tole S. J Neurosci 2013 33:6877-84.
Injury-independent induction of reactive gliosis in retinal Muller glia by loss of function of the LIM homeodomain transcription factor Lhx2
De Melo J, Miki K, Rattner A, Smallwood P, Hirokawa K, Monuki ES, Campochario P, and Blackshaw S. Proc Natl Acad Sci USA 2012 109:4657-62.