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Blackshaw Lab

Building and Rebuilding the Retina and Hypothalamus

  • Home
  • Research
  • Publications
  • Members
  • Datasets & Techniques
  • Home
  • Research
  • Publications
  • Members
  • Datasets & Techniques

Category: <span>Radial glia</span>

Multiple intrinsic factors act in concert with Lhx2 to direct retinal gliogenesis

Cell fate, Development, Lhx2, Muller glia, Neurogenesis, Notch/Delta, Radial glia, Retina, Signal transduction, Transcription factor

De Melo J, Clark BS, and Blackshaw S. Sci Reports 2016 6:32757.

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Lhx2 Is an Essential Factor for Retinal Gliogenesis and Notch Signaling

Cell fate, Development, Lhx2, Muller glia, Neurogenesis, Notch/Delta, Radial glia, Retina, Signal transduction, Transcription factor

De Melo J, Zibetti C, Clark BS, Hwang W, Miranda-Angulo AL, Qian J, Blackshaw S. J Neurosci 2016 36:2391-405.

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Rax-CreERT2 knock-in mice: a tool for selective and conditional gene deletion in progenitors and radial glia of the retina and hypothalamus

Cell lineage analysis, Hypothalamus, Radial glia, Retina, Tanycytes

Pak T, Yoo SY, Miranda-Angulo AM, Wang H, and Blackshaw S. PLoS ONE 2014, 9:e90381.

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Rax regulates hypothalamic tanycyte differentiation and barrier function in mice

Development, Radial glia, Tanycytes, Transcription factor

Miranda-Angulo AM, Byerly MS, Wang H, Messa J, Blackshaw S. J Comp Neurol 2013, 522:876-99.

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Tanycytes of the median eminence form a dietary-responsive neurogenic niche

Cell lineage analysis, Hypothalamus, Metabolism, Neurogenesis, Radial glia, Tanycytes

Lee DA, Pak T, Bedont JL, Wang H, Miranda-Angulo A, Takiar V, Charubhumi V, Balordi F, Takebayashi H, Fishell G, Ford E and Blackshaw S. Nat Neurosci 2012 15:700-2.

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Injury-independent induction of reactive gliosis in retinal Muller glia by loss of function of the LIM homeodomain transcription factor Lhx2

Lhx2, Muller glia, Neurodegeneration, Photoreceptor, Radial glia, Retina, Transcription factor

De Melo J, Miki K, Rattner A, Smallwood P, Hirokawa K, Monuki ES, Campochario P, and Blackshaw S. Proc Natl Acad Sci USA 2012 109:4657-62.

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Research Areas

  • AAV
  • Antibody specificity
  • ATAC-Seq
  • Autoimmune disease
  • Behavior
  • Book Chapter
  • Cell fate
  • Cell lineage analysis
  • Chemical senses
  • Chemogenetics
  • ChIP-Seq
  • Circadian
  • Commentary
  • D-Amino acids
  • Development
  • Diabetes
  • Extraretinal photoreceptors
  • FGF
  • Human genetics
  • Hypothalamus
  • In vivo electroporation
  • Lens
  • Lhx2
  • lncRNAs
  • Metabolism
  • Muller glia
  • Neural circuitry
  • Neural development
  • Neurodegeneration
  • Neurogenesis
  • Neurotransmitters
  • New technique
  • Nitric oxide
  • Notch/Delta
  • Nucleogenesis
  • Photoreceptor
  • Protein microarray
  • Proteomics
  • Protocol
  • Radial glia
  • Retina
  • Review article
  • RNA binding proteins
  • RNA splicing
  • RPE
  • SAGE
  • scRNA-Seq
  • Shh
  • Signal transduction
  • Sleep
  • Spatial patterning
  • SUMOylation
  • Suprachiasmatic nucleus
  • Tanycytes
  • Thalamus
  • Transcription factor
  • Transcriptomics
  • Visual cycle
  • Wnt

Recent Posts

  • Cell-specific regulation of gene expression using splicing-dependent frameshifting
  • Ectopic insert-dependent neuronal expression of GFAP promoter-driven AAV constructs in adult mouse retina
  • LRLoop: A method to predict feedback loops in cell-cell communication
  • Notch Inhibition Promotes Regeneration and Immunosuppression Supports Cone Survival in a Zebrafish Model of Inherited Retinal Dystrophy
  • Genetic loss of function of Ptbp1 does not induce glia-to-neuron conversion in retina

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