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Blackshaw Lab

Building and Rebuilding the Retina and Hypothalamus

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Category: <span>Retina</span>

D-Aspartate and D-Aspartate oxidase show selective and developmentally dynamic localization in mouse retina

D-Amino acids, Neurotransmitters, Retina

Huang AS, Lee DA, Blackshaw S. Exp Eye Res 2008 86:704-9.

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Development of vertebrate retina and hypothalamus

Development, Hypothalamus, Retina, Review article

Byerly MS, Blackshaw S. Wiley Interdisciplinary Reviews: Systems Biology and Medicine, 2009 1:380-9.

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“Developmental Genomics,” in Mechanisms of Retinal Development

Development, Retina, Review article

Blackshaw S. (Sernagor E, Eglen S, Harris W, Wong R. eds), Cambridge University Press 2006.

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Genomic analysis of mouse retinal development

Cell fate, Development, lncRNAs, Neurogenesis, Retina, SAGE, Transcriptomics

Blackshaw S, Harpavat S, Trimarchi J, Cai L, Huang H, Kuo WP, Weber G, Lee K, Fraioli RE, Cho S-H, Yung R, Asch E, Wong WH, Cepko CL. PLoS Biol 2004; 2:E247.

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The inherited blindness associated protein, AIPL1, interacts with the cell-cycle regulator protein, NUB1

Neurodegeneration, Photoreceptor, Retina

Akey DT, Zhu X, Dyer M, Li A, Sorensen A, Blackshaw S, Fukuda-Kamitani T, Daiger SP, Craft C, Kamitani T, Sohocki MM. Hum Mol Genet 2002 11:2723-33.

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Profile of the genes expressed in the human peripheral retina, macula, and retinal pigment epithelium determined through serial analysis of gene expression (SAGE)

Human genetics, Photoreceptor, Retina, SAGE, Transcriptomics

Sharon D*, Blackshaw S*, Cepko CL, Dryja TP. Proc Natl Acad Sci USA 2002 99:315-20 (* indicates equal contribution by both authors).

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Applying genomic technologies to neural development

Development, Retina, Review article, Transcriptomics

Blackshaw S, Livesey FJ. Current Opinion in Neurobiology. 2002 6:110-14.

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Comprehensive analysis of photoreceptor gene expression and the identification of candidate retinal disease genes

Human genetics, Neurodegeneration, Photoreceptor, Retina, SAGE, Transcriptomics

Blackshaw S, Fraioli RE, Furukawa T, Cepko CL. Cell 2001 107:579-89.

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Mutations in a new photoreceptor-pineal gene on 17p cause Leber’s congenital amaurosis

Human genetics, Neurodegeneration, Retina

Sohocki M M, Bowne SJ, Sullivan LS, Blackshaw S, Cepko CL, Payne AM, BhattacharyaSS, Khaliq S, Qasim Mehdi S, Birch DG, Harrison WR, Elder FF, Heckenlively JR, Daiger SP. Nat Genet 2000 24:79

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Research Areas

  • AAV
  • Antibody specificity
  • ATAC-Seq
  • Autoimmune disease
  • Behavior
  • Book Chapter
  • Cell fate
  • Cell lineage analysis
  • Chemical senses
  • Chemogenetics
  • ChIP-Seq
  • Circadian
  • Commentary
  • D-Amino acids
  • Development
  • Diabetes
  • Extraretinal photoreceptors
  • FGF
  • Human genetics
  • Hypothalamus
  • In vivo electroporation
  • Lens
  • Lhx2
  • lncRNAs
  • Metabolism
  • Muller glia
  • Neural circuitry
  • Neural development
  • Neurodegeneration
  • Neurogenesis
  • Neurotransmitters
  • New technique
  • Nitric oxide
  • Notch/Delta
  • Nucleogenesis
  • Photoreceptor
  • Protein microarray
  • Proteomics
  • Protocol
  • Radial glia
  • Retina
  • Review article
  • RNA binding proteins
  • RNA splicing
  • RPE
  • SAGE
  • scRNA-Seq
  • Shh
  • Signal transduction
  • Sleep
  • Spatial patterning
  • SUMOylation
  • Suprachiasmatic nucleus
  • Tanycytes
  • Thalamus
  • Transcription factor
  • Transcriptomics
  • Visual cycle
  • Wnt

Recent Posts

  • Cell-specific regulation of gene expression using splicing-dependent frameshifting
  • Ectopic insert-dependent neuronal expression of GFAP promoter-driven AAV constructs in adult mouse retina
  • LRLoop: A method to predict feedback loops in cell-cell communication
  • Notch Inhibition Promotes Regeneration and Immunosuppression Supports Cone Survival in a Zebrafish Model of Inherited Retinal Dystrophy
  • Genetic loss of function of Ptbp1 does not induce glia-to-neuron conversion in retina

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