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Blackshaw Lab

Building and Rebuilding the Retina and Hypothalamus

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Category: <span>scRNA-Seq</span>

Decomposing cell identity for transfer learning across platforms, tissues and species

ATAC-Seq, New technique, scRNA-Seq, Transcriptomics

Stein-O’Brien GL, Clark BS, Sherman T, Hu Q, Sealfon R, Wolf A, Zibetti C, Liu S, Qian J, Colantuoni C, Beer M, Blackshaw S, Goff LA, and Fertig EJ. Cell Systems, in press

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Comprehensive analysis of retinal development at single cell resolution identifies NFI factors as essential for mitotic exit and specification of late-born cells

Cell fate, Development, Neurogenesis, Retina, scRNA-Seq, Transcription factor, Transcriptomics

Clark BS, Stein-O’Brien GL, Shiau F, Cannon GH, Davis E, Sherman T, Rajaii F, James-Esposito RE, Gronostajski RM, Fertig EJ, Goff LA, and Blackshaw S. Neuron, in press.

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Tanycyte-independent regulation of hypothalamic leptin signaling

Hypothalamus, Metabolism, scRNA-Seq, Tanycytes

Yoo S, Cha D, Kim DW, Hoang T, and Blackshaw S. Frontiers in Neuroscience, in press.

Conditional deletion of DES1 in retina does not impair the visual cycle in cones

Photoreceptor, Retina, scRNA-Seq, Visual cycle

Kiser PD, Kolesnikov AV, Kiser JZ, Dong Z, Chaurasia B, Wang L, Summers SA, Hoang T, Blackshaw S, Peachey NS, Kefalov VJ, and Palczewski K. FASEB J 2019 fj201802493R. doi: 10.1096/fj.201802493R (e-pub ahead of print).

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Research Areas

  • AAV
  • Antibody specificity
  • ATAC-Seq
  • Autoimmune disease
  • Behavior
  • Book Chapter
  • Cell fate
  • Cell lineage analysis
  • Chemical senses
  • Chemogenetics
  • ChIP-Seq
  • Circadian
  • Commentary
  • D-Amino acids
  • Development
  • Diabetes
  • Extraretinal photoreceptors
  • FGF
  • Human genetics
  • Hypothalamus
  • In vivo electroporation
  • Lens
  • Lhx2
  • lncRNAs
  • Metabolism
  • Muller glia
  • Neural circuitry
  • Neural development
  • Neurodegeneration
  • Neurogenesis
  • Neurotransmitters
  • New technique
  • Nitric oxide
  • Notch/Delta
  • Nucleogenesis
  • Photoreceptor
  • Protein microarray
  • Proteomics
  • Protocol
  • Radial glia
  • Retina
  • Review article
  • RNA binding proteins
  • RNA splicing
  • RPE
  • SAGE
  • scRNA-Seq
  • Shh
  • Signal transduction
  • Sleep
  • Spatial patterning
  • SUMOylation
  • Suprachiasmatic nucleus
  • Tanycytes
  • Thalamus
  • Transcription factor
  • Transcriptomics
  • Visual cycle
  • Wnt

Recent Posts

  • Cell-specific regulation of gene expression using splicing-dependent frameshifting
  • Ectopic insert-dependent neuronal expression of GFAP promoter-driven AAV constructs in adult mouse retina
  • LRLoop: A method to predict feedback loops in cell-cell communication
  • Notch Inhibition Promotes Regeneration and Immunosuppression Supports Cone Survival in a Zebrafish Model of Inherited Retinal Dystrophy
  • Genetic loss of function of Ptbp1 does not induce glia-to-neuron conversion in retina

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