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Blackshaw Lab

Building and Rebuilding the Retina and Hypothalamus

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Category: <span>Signal transduction</span>

Methionine Adenosyltransferase (MAT): Adrenergic-cyclic AMP Mechanism Mediates Control of a Daily Rhythm in Pineal Expression

Circadian, Signal transduction

Kim JS, Coon SL, Blackshaw S, Cepko CL, Moller M, Mukda S, Zhao W-Q, Charlton CG, Klein DC. J Biol Chem 2005; 280:677-84.

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FK506 binding protein 12 is expressed in rat penile innervation and upregulated after cavernous nerve injury

Signal transduction

Sezen SF, Blackshaw S, Steiner JP, Burnett AL. Int J Impot Res 2002 14:506-12.

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PIKE: A novel nuclear GTPase that enchances PI3-kinase activity and is regulated by protein 4.1N

Signal transduction

Ye K, Hurt KJ, Wu FY, Fang M, Luo H, Hong JJ, Blackshaw S, Ferris, CD, Snyder SH. Cell 2000 103:919-30.

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Alteration of expression levels of neuronal nitric oxide synthase and haem oxygenase-2 messenger RNA in the hippocampi and corticies of young adult and aged cognitively unimpared and impared Long-Evans rats

Nitric oxide, Signal transduction

Law S, Dore S, Blackshaw S, Gauthier S, Quirion R. Neuroscience 2000 100:769-775.

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Heme oxygenase-2 acts to prevent neuronal death in brain cultures and following transient cerebral ischemia

Neurodegeneration, Signal transduction

Dore S, Goto S, Sampei K, Blackshaw S, Hester LD, Ingi T, Sawa A, Traystman RJ, Koehler RC, Snyder SH. Neuroscience 2000 99:587-92.

Link to Article>>

Poly(ADP-ribosylation basally activated by DNA strand breaks reflects glutamate-nitric oxide neurotransmission

New technique, Nitric oxide, Signal transduction

Pieper AA, Blackshaw S, Clements EE, Brat DJ, Krug DK, White AJ, Pinto-Garcia P, Favit A, Conover JR, Snyder SH, Verma A. Proc Natl Acad Sci USA 2000 97:1845-50

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Diabetic gastropathy in mice reflects loss of neuronal nitric oxide synthase that is restored by insulin

Diabetes, Neurotransmitters, Nitric oxide, Signal transduction

Watkins CC, Sawa A, Jaffrey SR, Blackshaw S, Barrow RK, Ferris CD, Snyder SH. J Clin Invest 2000 106:373-384

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Type 3 inositol 1,4,5-triphosphate receptor modulates cell death

Neurodegeneration, Signal transduction

Blackshaw S, Sawa A, Snyder SH, Khan A. FASEB J 2000 14:1375-1379.

Link to Article>>

Molecular and functional characterization of protein 4.1B, a novel member of the band 4.1 family with high level, focal expression in brain

Signal transduction

Parra M, Gascard P, Walensky LD, Gimm JA, Blackshaw S, Chan N, Takakuwa Y, Berger T, Lee G, Chasis J A, Snyder SH, Mohandas N, Conboy JG. J Biol Chem 2000 275:3247-55.

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Encephalopsin: A novel mammalian extraretinal opsin with discrete localizations in brain

Extraretinal photoreceptors, Signal transduction

Blackshaw S, Snyder SH. J Neurosci 1999 19:3681-90.

Link to Article>> View PDF>>

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Research Areas

  • AAV
  • Antibody specificity
  • ATAC-Seq
  • Autoimmune disease
  • Behavior
  • Book Chapter
  • Cell fate
  • Cell lineage analysis
  • Chemical senses
  • Chemogenetics
  • ChIP-Seq
  • Circadian
  • Commentary
  • D-Amino acids
  • Development
  • Diabetes
  • Extraretinal photoreceptors
  • FGF
  • Human genetics
  • Hypothalamus
  • In vivo electroporation
  • Lens
  • Lhx2
  • lncRNAs
  • Metabolism
  • Muller glia
  • Neural circuitry
  • Neural development
  • Neurodegeneration
  • Neurogenesis
  • Neurotransmitters
  • New technique
  • Nitric oxide
  • Notch/Delta
  • Nucleogenesis
  • Photoreceptor
  • Protein microarray
  • Proteomics
  • Protocol
  • Radial glia
  • Retina
  • Review article
  • RNA binding proteins
  • RNA splicing
  • RPE
  • SAGE
  • scRNA-Seq
  • Shh
  • Signal transduction
  • Sleep
  • Spatial patterning
  • SUMOylation
  • Suprachiasmatic nucleus
  • Tanycytes
  • Thalamus
  • Transcription factor
  • Transcriptomics
  • Visual cycle
  • Wnt

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  • Notch Inhibition Promotes Regeneration and Immunosuppression Supports Cone Survival in a Zebrafish Model of Inherited Retinal Dystrophy
  • Genetic loss of function of Ptbp1 does not induce glia-to-neuron conversion in retina

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