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Blackshaw Lab

Building and Rebuilding the Retina and Hypothalamus

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  • Research
  • Publications
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  • Research
  • Publications
  • Members
  • Datasets & Techniques

Category: <span>Spatial patterning</span>

Single cell RNA-Seq analysis identifies molecular mechanisms controlling hypothalamic patterning and differentiation

Hypothalamus, Neurogenesis, scRNA-Seq, Spatial patterning, TranscriptomicsHypothalamus, neurogenesis, scRNA-Seq, spatial patterning, transcriptomics

Kim DW, Washington PW, Wang ZQ, Lin S, Sun C, Jiang L, and Blackshaw S. Science, submitted.

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Canonical Wnt signaling regulates patterning, differentiation and nucleogenesis in mouse hypothalamus and prethalamus

Development, Hypothalamus, Signal transduction, Spatial patterning, Wnt

Newman EA, Wu D, Makoto MM, Zhang J, and Blackshaw S. Dev Biol, e-pub ahead of print.

Foxd1 is required for terminal differentiation of anterior hypothalamic neuronal subtypes

Development, Hypothalamus, Spatial patterning, Transcription factor

Newman EA, Wan J, Wang J, Jiang, Qian J, and Blackshaw S. Dev Biol 2018 439:102-111

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Molecular mechanisms controlling hypothalamic development

Development, Hypothalamus, Neurogenesis, Review article, Spatial patterning

Bedont JL, Blackshaw S, and Newman EA. Wiley Interdisciplinary Reviews: Developmental Biology, 2015 10.1002/wdev.18

Lhx2 is required for positioning of the eye field and patterning of the hypothalamus

Development, Hypothalamus, Lhx2, Retina, Spatial patterning

Roy A, de Melo J, Chaturvedi D, Thein T, Cabrera-Socorro A, Meyer G, Blackshaw S, Tole S. J Neurosci 2013 33:6877-84.

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A genomic atlas of mouse hypothalamic development

Development, Hypothalamus, Neurogenesis, Shh, Spatial patterning, Thalamus, Transcription factor, Transcriptomics

Shimogori T, Lee D A, Miranda-Angulo A, Yang Y, Yoshida A, Jiang L, Kataoka A, Wang H, Mashiko H, Avetisyan M A, Qi L, Qian J, and Blackshaw S. Nat Neurosci 2010 13:767-75.

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Research Areas

  • AAV
  • Antibody specificity
  • ATAC-Seq
  • Autoimmune disease
  • Behavior
  • Book Chapter
  • Cell fate
  • Cell lineage analysis
  • Chemical senses
  • Chemogenetics
  • ChIP-Seq
  • Circadian
  • Commentary
  • D-Amino acids
  • Development
  • Diabetes
  • Extraretinal photoreceptors
  • FGF
  • Human genetics
  • Hypothalamus
  • In vivo electroporation
  • Lens
  • Lhx2
  • lncRNAs
  • Metabolism
  • Muller glia
  • Neural circuitry
  • Neural development
  • Neurodegeneration
  • Neurogenesis
  • Neurotransmitters
  • New technique
  • Nitric oxide
  • Notch/Delta
  • Nucleogenesis
  • Photoreceptor
  • Protein microarray
  • Proteomics
  • Protocol
  • Radial glia
  • Retina
  • Review article
  • RNA binding proteins
  • RNA splicing
  • RPE
  • SAGE
  • scRNA-Seq
  • Shh
  • Signal transduction
  • Sleep
  • Spatial patterning
  • SUMOylation
  • Suprachiasmatic nucleus
  • Tanycytes
  • Thalamus
  • Transcription factor
  • Transcriptomics
  • Visual cycle
  • Wnt

Recent Posts

  • Cell-specific regulation of gene expression using splicing-dependent frameshifting
  • Ectopic insert-dependent neuronal expression of GFAP promoter-driven AAV constructs in adult mouse retina
  • LRLoop: A method to predict feedback loops in cell-cell communication
  • Notch Inhibition Promotes Regeneration and Immunosuppression Supports Cone Survival in a Zebrafish Model of Inherited Retinal Dystrophy
  • Genetic loss of function of Ptbp1 does not induce glia-to-neuron conversion in retina

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