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Blackshaw Lab

Building and Rebuilding the Retina and Hypothalamus

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Category: <span>SUMOylation</span>

Global identification of SUMO substrates reveals that crosstalk between SUMOylation and tyrosine phosphorylation promotes cell migration

Protein microarray, Proteomics, SUMOylation

Uzoma I, Hu J, Cox E, Xia S, Zhou J, Guzzo C, Paul C, Ajala O, Goodwin CR, Jeong JS, Zhang H, Meluh P, Blackshaw S, Matunis M, Qian J, and Zhu H. Mol Cell Proteomics 2018 17:871-888.

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Global analysis of SUMO-binding proteins identifies SUMOylation as a key regulator of the INO80 chromatin remodeling complex

Protein microarray, Proteomics, SUMOylation

Cox E, Hwang W, Hu J, Guzzo C, Uzoma I, Matunis M, Qian J, Zhu H and Blackshaw S. Mol Cell Proteomics 2017 16:812-823.

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Identification of SUMO E3 Ligase Specific Substrates Using Human Proteome Microarrays

Protein microarray, Proteomics, Protocol, SUMOylation

Cox E, Uzoma I, Guzzo CM, Jeong JS, Matunis M, Blackshaw S and Zhu H. Methods Mol Biol 2015 295:455-63.

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Characterization of the SUMO-binding activity of the myeloproliferative and mental retardation (MYM)-type zinc fingers in ZNF261 and ZNF198

Protein microarray, Proteomics, SUMOylation

Guzzo CM, Ringel A, Cox E, Uzoma I, Zhu H, Blackshaw S, Wolberger C, and Matunis MJ. 2014 PLoS ONE 2014 9:e105271.

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Pias3 directs rod photoreceptor development via SUMOylation of Nr2e3

Cell fate, Development, Photoreceptor, SUMOylation, Transcription factor

Onishi A, Peng GH, Du CH, Alexis U, Chen S, Blackshaw S. Neuron 2009 61:234-46.

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Research Areas

  • AAV
  • Antibody specificity
  • ATAC-Seq
  • Autoimmune disease
  • Behavior
  • Book Chapter
  • Cell fate
  • Cell lineage analysis
  • Chemical senses
  • Chemogenetics
  • ChIP-Seq
  • Circadian
  • Commentary
  • D-Amino acids
  • Development
  • Diabetes
  • Extraretinal photoreceptors
  • FGF
  • Human genetics
  • Hypothalamus
  • In vivo electroporation
  • Lens
  • Lhx2
  • lncRNAs
  • Metabolism
  • Muller glia
  • Neural circuitry
  • Neural development
  • Neurodegeneration
  • Neurogenesis
  • Neurotransmitters
  • New technique
  • Nitric oxide
  • Notch/Delta
  • Nucleogenesis
  • Photoreceptor
  • Protein microarray
  • Proteomics
  • Protocol
  • Radial glia
  • Retina
  • Review article
  • RNA binding proteins
  • RNA splicing
  • RPE
  • SAGE
  • scRNA-Seq
  • Shh
  • Signal transduction
  • Sleep
  • Spatial patterning
  • SUMOylation
  • Suprachiasmatic nucleus
  • Tanycytes
  • Thalamus
  • Transcription factor
  • Transcriptomics
  • Visual cycle
  • Wnt

Recent Posts

  • Cell-specific regulation of gene expression using splicing-dependent frameshifting
  • Ectopic insert-dependent neuronal expression of GFAP promoter-driven AAV constructs in adult mouse retina
  • LRLoop: A method to predict feedback loops in cell-cell communication
  • Notch Inhibition Promotes Regeneration and Immunosuppression Supports Cone Survival in a Zebrafish Model of Inherited Retinal Dystrophy
  • Genetic loss of function of Ptbp1 does not induce glia-to-neuron conversion in retina

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