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Blackshaw Lab

Building and Rebuilding the Retina and Hypothalamus

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Type 3 inositol 1,4,5-triphosphate receptor modulates cell death

Neurodegeneration, Signal transduction

Blackshaw S, Sawa A, Snyder SH, Khan A. FASEB J 2000 14:1375-1379.

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Molecular and functional characterization of protein 4.1B, a novel member of the band 4.1 family with high level, focal expression in brain

Signal transduction

Parra M, Gascard P, Walensky LD, Gimm JA, Blackshaw S, Chan N, Takakuwa Y, Berger T, Lee G, Chasis J A, Snyder SH, Mohandas N, Conboy JG. J Biol Chem 2000 275:3247-55.

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Mutations in a new photoreceptor-pineal gene on 17p cause Leber’s congenital amaurosis

Human genetics, Neurodegeneration, Retina

Sohocki M M, Bowne SJ, Sullivan LS, Blackshaw S, Cepko CL, Payne AM, BhattacharyaSS, Khaliq S, Qasim Mehdi S, Birch DG, Harrison WR, Elder FF, Heckenlively JR, Daiger SP. Nat Genet 2000 24:79

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Heme oxygenase-2 is neuroprotective in focal cerebral ischemia

Neurodegeneration, Neurotransmitters

Dore S, Sampi K, Goto S, Alkayed NJ, Blackshaw S, Gallagher M, Traysman RJ, Hurn PD, Guastella D, Koehler RC, Snyder SH. Mol Med 1999; 5:656-663.22.

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Encephalopsin: A novel mammalian extraretinal opsin with discrete localizations in brain

Extraretinal photoreceptors, Signal transduction

Blackshaw S, Snyder SH. J Neurosci 1999 19:3681-90.

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Circadian rhythm of patched1 transcription in the pineal regulated by adrenergic stimulation and cAMP

Circadian, Signal transduction

Borjigin J, Deng J, Wang MM, Li,X, Blackshaw S, Snyder SH. J Biol Chem 1999 274: 35012-35016.

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Differential expression of putative transbilayer amphipath transporters

Metabolism, Signal transduction

Halleck MS, Lawler JF Jr, Blackshaw S, Gao L, Nagarajan P, Hacker C, Pyle S, Nakanashi Y, Ando,H, Weinstock D, Williamson P, Schlegel RA. Physiol Genomics 1999 1:139-150.

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Serine racemase: a glial enzyme synthesizing D-serine to regulate glutamate-NMDA neurotransmission

D-Amino acids, Neurotransmitters, Signal transduction

Wolosker H, Blackshaw S, and Snyder SH. Proc Natl Acad Sci USA 1999 96:13409-14.

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Elimination of aggression in mice lacking endothelial nitric oxide synthetase

Behavior, Nitric oxide, Signal transduction

Demas GE, Kreigsfeld LJ, Blackshaw S, Nelson RJ, Snyder SH. J Neurosci 1999 RC30,1-5.

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A novel neuron-enriched homologue of the erythrocyte membrane cytoskeletal protein 4.1 is associated with synapses

Signal transduction

Walensky LD, Blackshaw S, Liao D, Watkins C, Weier H-UG, Huganir RL, Conboy J G, Mohandas N, Snyder SH. J Neurosci 1999 19:6457-6467.

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Research Areas

  • AAV
  • Antibody specificity
  • ATAC-Seq
  • Autoimmune disease
  • Behavior
  • Book Chapter
  • Cell fate
  • Cell lineage analysis
  • Chemical senses
  • Chemogenetics
  • ChIP-Seq
  • Circadian
  • Commentary
  • D-Amino acids
  • Development
  • Diabetes
  • Extraretinal photoreceptors
  • FGF
  • Human genetics
  • Hypothalamus
  • In vivo electroporation
  • Lens
  • Lhx2
  • lncRNAs
  • Metabolism
  • Muller glia
  • Neural circuitry
  • Neural development
  • Neurodegeneration
  • Neurogenesis
  • Neurotransmitters
  • New technique
  • Nitric oxide
  • Notch/Delta
  • Nucleogenesis
  • Photoreceptor
  • Protein microarray
  • Proteomics
  • Protocol
  • Radial glia
  • Retina
  • Review article
  • RNA binding proteins
  • RNA splicing
  • RPE
  • SAGE
  • scRNA-Seq
  • Shh
  • Signal transduction
  • Sleep
  • Spatial patterning
  • SUMOylation
  • Suprachiasmatic nucleus
  • Tanycytes
  • Thalamus
  • Transcription factor
  • Transcriptomics
  • Visual cycle
  • Wnt

Recent Posts

  • Cell-specific regulation of gene expression using splicing-dependent frameshifting
  • Ectopic insert-dependent neuronal expression of GFAP promoter-driven AAV constructs in adult mouse retina
  • LRLoop: A method to predict feedback loops in cell-cell communication
  • Notch Inhibition Promotes Regeneration and Immunosuppression Supports Cone Survival in a Zebrafish Model of Inherited Retinal Dystrophy
  • Genetic loss of function of Ptbp1 does not induce glia-to-neuron conversion in retina

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