RNA toxicity from the ALS/FTD C9ORF72 expansion is mitigated by antisense intervention

Neurodegeneration, Protein microarray, Proteomics, RNA binding proteins

Donnelly CJ, Zhang P, Pham JT, Heusler A, Mistry NA, Vidensky S, Daley EL, Poth EM, Hoover B, Fines DM, Margakis N, Tienari PJ, Petrucelli L, Traynor BJ, Wang J, Rigo F, Bennet CF, Blackshaw S, Sattler R, and Rothestein JD. Neuron 2013 80:415-28.

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Blackshaw Lab

Building and Rebuilding the Retina and Hypothalamus

RNA toxicity from the ALS/FTD C9ORF72 expansion is mitigated by antisense intervention