Notch Inhibition Promotes Regeneration and Immunosuppression Supports Cone Survival in a Zebrafish Model of Inherited Retinal Dystrophy

Muller glia, Neurodegeneration, Neurogenesis, Notch/Delta, Photoreceptor, Retina, scRNA-Seq, , , , , ,

Fogerty, J., Song, P., Boyd, P., Grabinski, S. E., Hoang, T., Reich, A., Cianciolo, L. T., Blackshaw, S., Mumm, J. S., Hyde, D. R., & Perkins, B. D. (2022). Notch Inhibition Promotes Regeneration and Immunosuppression Supports Cone Survival in a Zebrafish Model of Inherited Retinal Dystrophy. The Journal of neuroscience : the official journal of the Society for Neuroscience, 42(26), 5144–5158. https://doi.org/10.1523/JNEUROSCI.0244-22.2022

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In vivo base editing rescues cone photoreceptors in a mouse model of early-onset inherited retinal degeneration

Neurodegeneration, Photoreceptor, Retina, scRNA-Seq, , ,

Choi, E. H., Suh, S., Foik, A. T., Leinonen, H., Newby, G. A., Gao, X. D., Banskota, S., Hoang, T., Du, S. W., Dong, Z., Raguram, A., Kohli, S., Blackshaw, S., Lyon, D. C., Liu, D. R., & Palczewski, K. (2022). In vivo base editing rescues cone photoreceptors in a mouse model of early-onset inherited retinal degeneration. Nature communications, 13(1), 1830. https://doi.org/10.1038/s41467-022-29490-3

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Quantitative transportomics identifies Kif5a as a major regulator of neurodegeneration

Neurodegeneration, Retina,

Shah, S. H., Schiapparelli, L. M., Ma, Y., Yokota, S., Atkins, M., Xia, X., Cameron, E. G., Huang, T., Saturday, S., Sun, C. B., Knasel, C., Blackshaw, S., Yates, J. R., Cline, H. T., & Goldberg, J. L. (2022). Quantitative transportomics identifies Kif5a as a major regulator of neurodegeneration. eLife, 11, e68148. https://doi.org/10.7554/eLife.68148

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